2021年9月4日

“Off-label” use of drugs


前回はスパとトランスジェンダーについて話しました。心は女性でも身体は男性と一緒に裸になることに抵抗を持つ人も多いのは、まあ当然でしょう。

抵抗があると言えば、今いろいろ物議を醸しておりますイベルメクチンのコロナ治療について。これが今回のテーマです。本当に効くのか効かないのか?

そもそもイベルメクチンって日本ではコロナ治療薬として認められていないのですが、それでも使ったほうがいいのか、やめといたほうがいいのか。目的外でも効けばいいじゃん、使わせてよ!という人、やっぱり薬はきちんと目的に沿って処方すべきだという人、政府としてどう対応するかという問題もあります。こちらも意見が分かれそうですね!

あなたの意見はどちらでしょう?

Topic 1. “Furusato Nouzei“ (hometown taxation)

Q1. Do you use “Furusato Nouzei” system? Why and why not?

Q2. Which town do you want to pay your tax to? Why?

Q3. What is the purpose of “Furusato Nouzei”?

Q4. Do you think “Furusato Nouzei” system can correct the tax revenue gap between local governments? If not, what is the possible solution?

Topic 2. “Off-label” use of drugs

Q1. “Off-label” use is to use approved drugs in unapproved indications or dosage. So the effect is not guaranteed and unexpected side effects may occur. It can be prescribed at the discretion of the doctor, and basically not covered by insurance.
What is Pros and Cons of “off-label” use?

Q2. Ivermectin is an anti-parasitic drug. According to some reports, ivermectin is highly effective to treat COVID-19 and has been approved in some countries. In Japan, ivermectin has not been approved to treat COVID-19 but is used “off-label” and is covered by insurance. Some doctors prescribe it during home care.
Would you like to use ivermectin if you get infected COVID-19? If yes, do you want to use it at a hospital or during home care?

Q3. Global health experts have warned that clinical trials were still needed to establish the efficacy of ivermectin for COVID-19. Do you think Japan should continue to use ivermectin for COVID-19 as “off-label" use or should it be prohibited?

Q4. “Off-label” use may be required for diseases for which there is no cure or for which the best treatment is frequently updated. On the other hand, inappropriate “off-label” use such as for beauty purposes, should be avoided. How can we avoid inappropriate “off-label” use, and not interfere with proper “off-label” use?

https://www3.nhk.or.jp/nhkworld/en/news/20210824_09/

https://www.freemalaysiatoday.com/category/nation/2021/06/25/hospitals-can-apply-for-off-label-use-of-ivermectin-says-health-ministry/?__cf_chl_jschl_tk__=pmd_X0B0BkvTHJB7Aa291jlGKsHGv6Qh2rvWV3hge3SSWhA-1630169748-0-gqNtZGzNAxCjcnBszQ2